MAF Family Gene

Preferred Label : MAF Family Gene;

NCIt synonyms : MAF Gene;

NCIt definition : Maf family proteins possess a highly conserved basic leucine zipper (bZip) domain and are subdivided into large and small Maf proteins. The Maf family proteins appear to regulate cell differentiation processes and also cellular functions as partner molecules of CNC family proteins.;

NCIt note : MAF proteins have been reported to be able to bind with FOS proteins to form the AP-1 transcription factor (from Nature Cell Biol. 4: E131-E136, 2002 via OMIM);

NCI Metathesaurus CUI : CL448419;

Details

Origin ID

C18545;

UMLS CUI

C0919481;

Semantic type(s)
- Gene or Genome [UMLS semantic type]
UMLS correspondences (same concept)
- MAF bZIP transcription factor [HGNC gene]
- Maf bzip transcription factor [OMIM gene]
gene_encodes_gene_product
- MAF Family Protein [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_involved_in_molecular_abnormality
- MAF Family Gene Translocation [NCIt concept]
- t(14;16)(q32;q23) [NCIt concept]
- t(14;20)(q32;q12) [NCIt concept]
gene_plays_role_in_process
- DNA Binding [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients