Preferred Label : Antibody-drug Conjugate SHR-A1912;
NCIt synonyms : ADC SHR-A1912;
NCIt definition : An antibody-drug conjugate (ADC) composed of a monoclonal antibody against an unnamed
tumor-associated antigen (TAA) linked to an as of yet undisclosed cytotoxic agent,
with potential antineoplastic activity. Upon intravenous administration, the monoclonal
antibody moiety of SHR-A1912 targets and binds to the TAA expressed on tumor cells.
Upon binding and internalization, the cytotoxic agent is released and kills the TAA-expressing
cancer cells, through an as of yet unknown mechanism of action.;
Molecule name : SHR A1912; SHR-A1912;
NCI Metathesaurus CUI : CL1773824;
Origin ID : C185413;
UMLS CUI : C5666987;
Semantic type(s)
- concept_is_in_subset
