NCIt definition : A long-acting pegylated form of a recombinant therapeutic agent which is chemically
identical to or similar to an endogenous human granulocyte colony-stimulating factor
(G-CSF). Produced endogenously by monocytes, fibroblasts, and endothelial cells, G-CSF
binds to and activates specific cell surface receptors, stimulating neutrophil progenitor
proliferation and differentiation and selected neutrophil functions. Conjugation of
the cytokine with a branched polyethylene glycol molecule (pegylation) significantly
increases its therapeutic half-life. (NCI04);
Alternative definition : NCI-GLOSS: A drug used to increase numbers of white blood cells in patients who are
receiving chemotherapy. It is a type of colony-stimulating factor.;
UNII : 3A58010674;
CAS number : 208265-92-3;
Drug name : Neulasta; Neulastim; Fulphila; Jinyouli; Ziextenzo; Nyvepria; Pegcyte; Udenyca; Neupopeg; G-Lasta; Dulastin; Stimufend; Fylnetra;