Preferred Label : Anti-HPV16 TCR-engineered T-cells CRTE7A2-01;
NCIt synonyms : Anti-HPV16 TCR T Cells CRTE7A2-01; Anti-HPV16 TCR-T Cells CRTE7A2-01;
NCIt definition : A preparation of T-lymphocytes that has been genetically modified to express a T-cell
receptor (TCR) specific for an as of yet not identified viral oncoprotein(s) of human
papillomavirus type 16 (HPV16), with potential antineoplastic activity. Upon intravenous
administration, the anti-HPV16 TCR-engineered T-cells CRTE7A2-01 specifically recognize
and bind to the HPV16 oncoprotein(s) expressed on tumor cells. This may lead to cytotoxic
T-lymphocyte (CTL)-mediated elimination of tumor cells expressing the HPV16 oncoprotein(s).;
Molecule name : CRTE7A2 01; CRTE7A2-01;
NCI Metathesaurus CUI : CL1773808;
Origin ID : C185397;
UMLS CUI : C5666980;
Semantic type(s)
- Cell [UMLS semantic type]
- concept_is_in_subset
