H3.3 K27I Variant

Preferred Label : H3.3 K27I Variant;

NCIt synonyms : Histone H3.3 K27I; NP_002098.1:p.Lys28Ile; NP_002098.1:p.K28I; H3.3 p.Lys28Ile; H3.3 p.K28I; Histone H3.3 Lys28Ile; Histone H3.3 K28I; H3.3 K28I Variant; Histone H3.3 K27I Mutation; Histone H3.3 K28I Mutation; Histone H3.3 Lys27Ile Mutation; Histone H3.3 Lys28Ile Mutation; H3.3 K27I Mutation; H3.3 NP_002098.1:p.Lys28Ile; H3.3 K28I Mutation; H3.3 Lys27Ile Mutation; H3.3 Lys28Ile Mutation; H3.3 NP_002098.1:p.K28I; Histone H3.3 Lys27Ile;

NCIt definition : A change in the amino acid residue at position 27 in histone H3.3 protein where lysine has been replaced by isoleucine.;

NCIt note : Even though the literature refers to lysine 27 methylation or amino acid variation/mutation, RefSeq indicates that the lysine is located at amino acid position 28 in histone H3. (see https://link.springer.com/article/10.1007/s00401-018-1867-2);

NCI Metathesaurus CUI : CL1773796;

PubMed : 26399631;

Details

Origin ID

C185380;

UMLS CUI

C5669886;

Semantic type(s)
- Cell or Molecular Dysfunction [UMLS semantic type]
gene_product_variant_of_gene_product
- Histone H3 [NCIt concept]
- Histone H3.3 [NCIt concept]
molecular_abnormality_involves_gene
- Histone H3 Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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