Preferred Label : Anti-Wolbachia Agent AWZ1066S;
NCIt related terms : AWZ-1066S;
NCIt definition : An orally bioavailable synthetic compond that is active against the bacterium Wolbachia
and that can potentially be used to treat diseases caused by namatodes of the family
Filariodidea, such as lymphatic filariasis and onchocerciasis. Upon oral administration,
the anti-Wolbachia agent AWZ1066S specifically kills Wolbachia through an as of yet
not fully identified mechanism of action (MoA). In filarial nematodes-infected humans,
adult worms need Wolbachia in order to grow, reproduce, and survive. Targeting Wolbachia
may indirectly kill the adult parasitic worms and prevent filariasis.;
UNII : XQ75265YHR;
CAS number : 2239272-16-1;
Molecule name : AWZ 1066S; AWZ-1066S;
NCI Metathesaurus CUI : CL1773385;
Origin ID : C185291;
UMLS CUI : C5666970;
Semantic type(s)
- concept_is_in_subset
