SARS-CoV-2 Protein Subunit Vaccine AKS-452

Preferred Label : SARS-CoV-2 Protein Subunit Vaccine AKS-452;

NCIt synonyms : Fc Fusion COVID-19 Subunit Vaccine AKS-452; COVID-19 Vaccine AKS-452; SARS-CoV-2 Vaccine AKS-452;

NCIt definition : An engineered protein subunit vaccine composed of an Fc fusion protein of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) spike (S) protein receptor binding domain (RBD) antigen and human immunoglobulin G1 (IgG1) Fc, with potential immunizing activity against SARS-CoV-2. Upon administration of the SARS-CoV-2 protein subunit vaccine AKS-452, the S protein activates the immune system to create anti-SARS-CoV-2 S protein antibodies. The antibodies recognize and neutralize the S protein and kill SARS-CoV-2. This prevents SARS-CoV-2 infection. S protein, usually found on the surface of SARS-CoV-2, plays an essential role in the infection pathway of the SARS-CoV-2 virus.;

Molecule name : AKS 452; AKS-452;

NCI Metathesaurus CUI : CL1773442;

Details

Origin ID

C185228;

UMLS CUI

C5666960;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- AKS-452 COVID-19 vaccine [MeSH Supplementary Concept]
chemical_or_drug_has_mechanism_of_action
- Antigen Sensitization [NCIt concept]
concept_is_in_subset
- NCIt COVID-19 Agent Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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