Plasma Cell Myeloma-Induced Bone Disease

Preferred Label : Plasma Cell Myeloma-Induced Bone Disease;

NCIt synonyms : MBD; Myeloma Bone Disease; Multiple Myeloma-Induced Bone Disease;

NCIt definition : Bone infiltration by malignant plasma cells in patients with history of plasma cell myeloma. Bone involvement occurs in approximately eighty percent of newly diagnosed symptomatic plasma cell myeloma patients. The axial skeleton, particularly the spine, and the proximal long bones are the most commonly affected bone sites. It results in osteolytic bone lesions, widespread osteopenia, and compression fractures.;

Neoplastic status : Malignant;

NCI Metathesaurus CUI : CL1773503;

Details

Origin ID

C185156;

UMLS CUI

C5575689;

Automatic exact mappings (from CISMeF team)
- Attention deficit hyperactivity disorder (disorder) [SNOMED CT concept]
- Marchiafava-Bignami disease [ORDO Disease]
Disease excludes normal cell origin
- Bone Marrow Stem Cell [NCIt concept]
Disease may have findings
- Compression Fracture [NCIt concept]
- Osteolytic Lesions of Multiple Myeloma [NCIt concept]
- Osteopenia [NCIt concept]
- Pathologic Fracture [NCIt concept]
Has associated anatomic sites
- Bone [NCIt concept]
- Connective and Soft Tissue [NCIt concept]
- Musculoskeletal System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Indolent Clinical Course [NCIt concept]
disease_has_abnormal_cell
- Malignant Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
disease_has_associated_disease
- Multiple Myeloma [NCIt concept]
disease_has_finding
- Malignant Cellular Infiltrate [NCIt concept]
- Metastatic Lesion [NCIt concept]
- Secondary Lesion [NCIt concept]
disease_has_metastatic_anatomic_site
- Bone [NCIt concept]

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