Oncogene EGF - CISMeF

Preferred Label : Oncogene EGF;

NCIt synonyms : URG;

NCIt definition : Human Oncogene EGF is a mutated variant of EGF Gene, which encodes Epidermal Growth Factor, a 53-aa peptide hormone with profound effects on cell differentiation and potent mitogenic effects on a variety of ectodermal and mesodermal cells. The EGF precursor is believed to exist as a membrane-bound molecule that is proteolytically cleaved to generate the hormone. Oncogene EGF disrupts normal cell function.;

GenBank Accession Number : AF023155;

Details

Origin ID

C18494;

UMLS CUI

C0919420;

OMIM relation
- Epidermal growth factor [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
allele_in_chromosomal_location
- 4q25 [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_plays_role_in_process
- Cell Differentiation Process [NCIt concept]
- Cell Proliferation [NCIt concept]
- Signal Transduction [NCIt concept]
- Tumorigenesis [NCIt concept]

Keyword's position in hierarchy(ies) :

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