NCIt synonyms : E26 Transformation Specific Oncogene; ETS;
NCIt definition : Oncogene ETS was originally discovered as a chimeric component, along with a truncated
v-myb gene, in the genome of E26, an avian leukosis virus. ETS1 encodes 42-52 kD nuclear
phosphoprotein transcription factors that interact with purine-rich promoter/enhancer
sequences in the TCRA gene. ETS1 also regulates p16(INK4A) gene expression. The human
gene is located at 11q23.3.;