HER2/CEP17 FISH Ratio Assay

Preferred Label : HER2/CEP17 FISH Ratio Assay;

NCIt synonyms : HER2/CEP17 Ratio; HER2/CEP17 Dual-Probe Fluorescence In Situ Hybridization Ratio Assay; HER2/CEP17 Ratio Assay; HER2/CEP17 Ratio Measurement; HER2/CEP17 Fluorescence In Situ Hybridization Ratio Assay; ERBB2/CEP17 FISH Ratio Assay;

NCIt related terms : ERBB2 gene copy number/Chromosome 17 copy number in Tissue by FISH;

NCIt definition : A dual-probe fluorescent in situ hybridization-based assay used to determine the ratio of signal intensity present in a sample for two probes, one that is specific for ERBB2 (HER2) expression and one that is specific for chromosome 17 centromeric sequences (CEP17). Since the HER2 gene is present on chromosome 17, ratios greater than 1 indicate gene amplification or mRNA overexpression for HER2.;

NCI Metathesaurus CUI : CL1772551;

Codes from synonyms : 49683-6;

Details

Origin ID

C184370;

UMLS CUI

C5669237;

Semantic type(s)
- Molecular Biology Research Technique [UMLS semantic type]
concept_is_in_subset
- mCode Terminology [NCIt concept]
- mCode Tumor Marker Test Value Set [NCIt concept]
related_to_genetic_biomarker
- ERBB2 Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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