Preferred Label : Oncogenes, Protein-Kinase;
NCIt synonyms : Protein-Kinase Oncogene;
NCIt definition : Human Protein-Kinase Oncogenes are mutated variants of Kinase Family Genes, which
encode diverse Protein Kinases. Protein kinase enzymes catalyze the conversion of
a protein to a phosphoprotein by covalently transferring the terminal, gamma phosphate
group from ATP to a variety of substrates that typically play key regulatory roles
in diverse cellular functions. Protein-Kinase oncogenes disrupt normal cell function.;
Origin ID : C18343;
UMLS CUI : C0812220;
Semantic type(s)
- gene_found_in_organism
- gene_plays_role_in_process
