NCIt definition : Human transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
(TFAP2A) gene, located at 6p24, encodes transcription factor AP-2 alpha. This gene
is developmentally regulated and expression is induced by retinoic acid. Alternative
splicing of the AP2 gene produces four mRNA transcripts, resulting in four protein
isoforms. One of these proteins is a negative regulator of transcriptional activation
by AP-2.;