Alpha-lactalbumin Breast Cancer VaccineNCIt concept
Preferred Label : Alpha-lactalbumin Breast Cancer Vaccine;
NCIt synonyms : Alpha-lactalbumin Vaccine; a-Lactalbumin Vaccine; Alpha-lactalbumin Protein Vaccine; aLA Breast Cancer Vaccine;
NCIt definition : A breast cancer vaccine consisting of recombinant human alpha-lactalbumin (aLA), with
potential immunostimulatory and antineoplastic activities. Upon administration, aLA
breast cancer vaccine may stimulate the immune system to mount a cytotoxic T-lymphocyte
(CTL) response against tumor cells that express the aLA protein, resulting in tumor
cell lysis. aLA is expressed in many types of breast cancer, including triple negative
breast cancer (TNBC), while normally present in healthy breast tissues only during
lactation.;