Alpha-lactalbumin Breast Cancer Vaccine

Preferred Label : Alpha-lactalbumin Breast Cancer Vaccine;

NCIt synonyms : Alpha-lactalbumin Vaccine; a-Lactalbumin Vaccine; Alpha-lactalbumin Protein Vaccine; aLA Breast Cancer Vaccine;

NCIt definition : A breast cancer vaccine consisting of recombinant human alpha-lactalbumin (aLA), with potential immunostimulatory and antineoplastic activities. Upon administration, aLA breast cancer vaccine may stimulate the immune system to mount a cytotoxic T-lymphocyte (CTL) response against tumor cells that express the aLA protein, resulting in tumor cell lysis. aLA is expressed in many types of breast cancer, including triple negative breast cancer (TNBC), while normally present in healthy breast tissues only during lactation.;

NCI Metathesaurus CUI : CL1771391;

Détails

Origin ID

C183167;

UMLS CUI

C5668180;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
chemical_or_drug_has_mechanism_of_action
- Antigen Sensitization [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Alpha-Lactalbumin [NCIt concept]

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