Lipid Nanoparticle-encapsulated SARS-CoV-2 mRNA Vaccine PTX-COVID19-B

Preferred Label : Lipid Nanoparticle-encapsulated SARS-CoV-2 mRNA Vaccine PTX-COVID19-B;

NCIt synonyms : LNP-encapsulated SARS-CoV-2 mRNA Vaccine PTX-COVID19-B;

NCIt definition : A vaccine consisting of a lipid nanoparticle (LNP) encapsulating a messenger RNA (mRNA) encoding a full-length version of the spike (S) protein of SARS-CoV-2, with potential immunizing activity against SARS-CoV-2. Upon administration of the LNP-encapsulated SARS-CoV-2 mRNA vaccine PTX-COVID19-B, the lipid nanoparticle binds to the plasma membrane of cells and releases the mRNA into the cells. The mRNA is then translated by ribosomes to produce the SARS-CoV-2 S protein. This may activate both humoral and cellular immune responses which may result in protection against SARS-CoV-2 infection.;

Molecule name : PTX-COVID19-B;

NCI Metathesaurus CUI : CL1770601;

Details

Origin ID

C182103;

UMLS CUI

C5666881;

Semantic type(s)
- Immunologic Factor [UMLS semantic type]
- Nucleic Acid, Nucleoside, or Nucleotide [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- PTX-COVID19-B COVID-19 vaccine [MeSH Supplementary Concept]
concept_is_in_subset
- NCIt COVID-19 Agent Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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