Preferred Label : Autologous Tumor Killer Cells;
NCIt synonyms : Co-cultured Autologous NK Cells and gdT Cells; Autologous TKCs; Autologous NK Cells/gamma-delta-T Cells; Autologous NK/gd-T Cells;
NCIt definition : A preparation of autologous tumor killer cells (TKCs) which consists of the innate
immune cells natural killer (NK) cells and gamma delta T (gdT) cells, which are T-lymphocytes
that express only gamma chain and delta chain T-cell receptors (TCRs), with potential
cytolytic and antineoplastic activities. NK cells and gdT cells are isolated from
the patients' peripheral blood mononuclear cells (PBMCs) and co-cultured ex vivo in
a certain proportion with TKC technology. Upon administration, autologous TKCs may
lyse cancer cells, and further stimulate an anti-tumor immune response.;
NCI Metathesaurus CUI : CL1664822;
Origin ID : C182001;
UMLS CUI : C5557410;
Semantic type(s)
- Cell [UMLS semantic type]
- concept_is_in_subset
