Preferred Label : Personalized Cancer Neoantigen Vaccine MVA-PEV;
NCIt synonyms : Personalized Vaccine MVA-PEV; Booster Vaccine MVA-PEV; Modified Vaccinia Ankara Tumor- specific Neoantigen Boosting Vaccine MVA-PEV; Nous-PEV Booster Vaccine MVA-PEV;
NCIt definition : A personalized neoantigen booster vaccine comprised of a modified Vaccinia Ankara
(MVA) viral vector encoding numerous patient-specific tumor neoantigens, which are
identified based on patient-specific tumor mutations obtained from the individual's
tumor, with potential immunostimulatory and antineoplastic activities. The neoantigens
are the same as the ones in the priming vaccine GAd-PEV. Following administration
of the priming vaccine GAd-PEV, the administration of the booster vaccine, personalized
cancer neoantigen vaccine MVA-PEV, may further enhance CD8 and CD4 neoantigen-specific
T-cell responses against the patient's tumor cells expressing the neoantigens.;
Molecule name : MVA-PEV;
NCI Metathesaurus CUI : CL1664824;
Origin ID : C181999;
UMLS CUI : C5557408;
Semantic type(s)
- concept_is_in_subset
