Graft-vs-Leukemia Effect

Preferred Label : Graft-vs-Leukemia Effect;

NCIt synonyms : Graft-Versus-Leukemia Effect; GVL;

NCIt definition : an advantageous side-effect of a graft-vs-host reaction in which a leukemia patient is first irradiated to kill residual leukemic cells and is then given a bone marrow graft to replenish the immune system. If cytotoxic T cells are not depleted from the bone marrow graft, these alloreactive T cells can attack the host's cells (graft-vs-host reaction) but can also attack the host's residual leukemic cells, thereby assisting in preventing recurrence of disease.;

Details

Origin ID

C18156;

UMLS CUI

C0600554;

Currated CISMeF NLP mapping
- graft vs leukemia effect [MeSH Descriptor]
- graft vs leukemia effect [MeSH concept]
Semantic type(s)
- Organ or Tissue Function [UMLS semantic type]
UMLS correspondences (same concept)
- graft vs leukemia effect [MeSH concept]
- graft vs leukemia effect [MeSH Descriptor]
biological_process_has_initiator_chemical_or_drug
- Antigen [NCIt concept]
biological_process_is_part_of_process
- Immunity [NCIt concept]

Keyword's position in hierarchy(ies) :

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