Preferred Label : Graft-vs-Leukemia Effect;
NCIt synonyms : Graft-Versus-Leukemia Effect; GVL;
NCIt definition : an advantageous side-effect of a graft-vs-host reaction in which a leukemia patient
is first irradiated to kill residual leukemic cells and is then given a bone marrow
graft to replenish the immune system. If cytotoxic T cells are not depleted from the
bone marrow graft, these alloreactive T cells can attack the host's cells (graft-vs-host
reaction) but can also attack the host's residual leukemic cells, thereby assisting
in preventing recurrence of disease.;
Origin ID : C18156;
UMLS CUI : C0600554;
Currated CISMeF NLP mapping
- Semantic type(s)
- UMLS correspondences (same concept)
