Preferred Label : Chromosome Painting;
NCIt definition : Refers to the hybridization of fluorescently labeled, chromosome-specific, composite
probe pools to cytological preparations. It allows the visualization of individual
chromosomes in metaphase or interphase cells and the identification of both numerical
and structural chromosomal aberrations with high sensitivity and specificity. Chromosome
painting can be applied to cross-species comparisons as well as to the study of chromosomal
rearrangements. The simultaneous hybridization of multiple chromosome painting probes,
each tagged with a specific fluorochrome or fluorochrome combination, has resulted
in the differential color display of chromosomes, i.e. spectral or color karyotyping.
(From Ried et al 1998 Hum Mol Genet 7:1619);
Origin ID : C18154;
UMLS CUI : C0600509;
Currated CISMeF NLP mapping
- Semantic type(s)
- UMLS correspondences (same concept)
