Preferred Label : Sodium Dodecylsulfate-Polyacrylamide Gel Electrophoresis;
NCIt synonyms : Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis; SDS-PAGE;
NCIt definition : Sodium dodecyl sulfate (SDS) polyacrylamide gel electrophoresis is a procedure for
estimating molecular weights of polypeptides, and uses SDS, a detergent that dissociates
and unfolds oligomeric proteins into its subunits. The SDS binds to the polypeptides
to form complexes with fairly constant charge to mass ratios. The electrophoretic
migration rate through a gel is therefore determined only by the size of the complexes.;
Origin ID : C18150;
UMLS CUI : C0600209;
Automatic exact mappings (from CISMeF team)
- Semantic type(s)
- UMLS correspondences (same concept)
