Preferred Label : Functional Microbial-induced Antibody Measurement;
NCIt related terms : MBFAB; Functional Microbial-induced Antibody;
NCIt definition : The determination of the functional binding of microbial-induced antibody in a biospecimen.
A functional microbial-induced antibody is defined as antibodies that have agonist
or antagonist effects on pathogens or their toxins in the presence of other effector
molecules or cells. For example, the effects of functional antibodies can include
neutralization, phagocytosis, antibody-dependent cellular cytotoxicity, and complement-mediated
lysis. The production of this antibody may be triggered by naturally occurring infection
and/or vaccination using a whole microbe or component(s) of a microbe.;
Alternative definition : CDISC: A measurement of the functional binding microbial-induced antibody in a biological
specimen. A functional microbial-induced antibody is defined as antibodies that have
agonist or antagonist effects on pathogens or their toxins in the presence of other
effector molecules or cells. For example, the effects of functional antibodies can
include neutralization, phagocytosis, antibody-dependent cellular cytotoxicity, and
complement-mediated lysis. The production of this antibody may be triggered by naturally
occurring infection, vaccination and/or viral vector-based therapy using a whole microbe
or component(s) of a microbe.;
NCI Metathesaurus CUI : CL1664516;
Origin ID : C181395;
UMLS CUI : C5557052;
Semantic type(s)
- concept_is_in_subset
