METTL3 wt Allele

Preferred Label : METTL3 wt Allele;

NCIt synonyms : AdoMet-Binding Subunit of the Human mRNA (N6-Adenosine)-Methyltransferase Gene; IME4; MTA70; MT-A70; M6A; mRNA (2'-O-Methyladenosine-N(6)-)-Methyltransferase Gene; mRNA M(6)A Methyltransferase Gene; Methyltransferase Like 3 wt Allele; IME4, S. cerevisiae, Homolog of Gene; Spo8; hMETTL3; Methyltransferase-Like 3 Gene;

NCIt definition : Human METTL3 wild-type allele is located in the vicinity of 14q11.2 and is approximately 13 kb in length. This allele, which encodes N6-adenosine-methyltransferase catalytic subunit protein, plays a role in the regulation of mRNA stability, translation and editing.;

NCI Metathesaurus CUI : CL1663693;

GenBank Accession Number : AF014837;

Details

Origin ID

C181096;

UMLS CUI

C5551146;

Automatic exact mappings (from CISMeF team)
- Acute erythroid leukemia [ICD-11 Extension code]
- Methyltransferase 3, n6-adenosine-methyltransferase complex catalytic subunit [OMIM gene]
OMIM relation
- Methyltransferase 3, n6-adenosine-methyltransferase complex catalytic subunit [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 14q11.2 [NCIt concept]
gene_plays_role_in_process
- Methylation [NCIt concept]
- RNA Processing [NCIt concept]
- Translational Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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