PKA Regulatory Subunit RIalpha Mixed-Backbone Antisense Oligonucleotide GEM 231

Preferred Label : PKA Regulatory Subunit RIalpha Mixed-Backbone Antisense Oligonucleotide GEM 231;

NCIt synonyms : Gene Expression Modulator 231;

NCIt related terms : GEM 231;

NCIt definition : A mixed backbone oligonucleotide exhibiting antitumor activity. GEM-231 is complementary to the RI alpha subunit of Protein Kinase A (PKA), resulting in downregulation of PKA expression and ultimately tumor growth. (NCI);

Alternative definition : NCI-GLOSS: A drug that may inhibit the growth of malignant tumors.;

Molecule name : GEM 231; GEM-231;

Codes from synonyms : CDR0000045949;

Details

Origin ID

C1810;

UMLS CUI

C0677981;

Automatic exact mappings (from CISMeF team)
- GEM231 [MeSH Supplementary Concept]
- GEM231 [MeSH concept]
Semantic type(s)
- Nucleic Acid, Nucleoside, or Nucleotide [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- GEM231 [MeSH Supplementary Concept]
- GEM231 [MeSH concept]
concept_is_in_subset
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
is_component_of_chemotherapy_regimen
- Docetaxel/GEM 231 [NCIt concept]
- GEM 231/Paclitaxel [NCIt concept]

Keyword's position in hierarchy(ies) :

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