NCIt synonyms : Gain of Function EGFR Exon 20 Gene Mutation; Gain of Function EGFR Exon 20 Mutation; Activating HER1 Exon 20 Mutation; EGFR Exon 20 Activating Mutation; EGFR Exon 20 Gain of Function Gene Mutation; Activating Epidermal Growth Factor Receptor Exon 20 Mutation; Activating EGFR Exon 20 Gene Mutation; Activating ERBB Exon 20 Mutation; EGFR Exon 20 Gain of Function Mutation; Activating ERBB1 Exon 20 Mutation; EGFR Exon 20 Activating Gene Mutation;
NCIt definition : A molecular genetic abnormality indicating the presence of a mutation in exon 20 of
the EGFR gene that results in constitutive epidermal growth factor receptor-dependent
signal transduction and activation of downstream signaling pathways.;