Neutrophil Extracellular Trap

Preferred Label : Neutrophil Extracellular Trap;

NCIt synonyms : NET;

NCIt definition : A network of extracellular fibrillar structures containing granule proteins, chromatin fibers and DNA that are released by neutrophils as part of the host defense response. Extracellular release of antimicrobial proteins such as neutrophil elastase, cathepsin G and histones can bind, disarm, and kill microbes independent of phagocytosis and the fibrillar nature of these structures may target these effects locally by preventing diffusion of these proteins outside the target site.;

Details

Origin ID

C180931;

UMLS CUI

C3850088;

Anatomic structure is physical part of
- Extracellular Space [NCIt concept]
Automatic exact mappings (from CISMeF team)
- Elk3, ets-domain protein [OMIM gene]
- Ephrin receptor ephb1 [OMIM gene]
- Extracellular Traps [MeSH Descriptor]
- Neutrophil Extracellular Traps [MeSH concept]
- Solute carrier family 6 (neurotransmitter transporter, noradrenaline), member 2 [OMIM gene]
- solute carrier family 6 member 2 [ORDO Gene]
Semantic type(s)
- Cell Component [UMLS semantic type]
UMLS correspondences (same concept)
- Neutrophil Extracellular Traps [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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