Samarium Sm-153

Preferred Label : Samarium Sm-153;

NCIt synonyms : Sm-153; 153Sm; Samarium, Isotope of Mass 153; Samarium-153;

NCIt related terms : samarium 153;

NCIt definition : A beta- and gamma-emitting isotope, with antineoplastic activity. Emitted by samarium Sm 153, beta particles directly damage cellular DNA and, by ionizing intracellular water to produce several types of cytotoxic free radicals and superoxides, indirectly damage intracellular biological macromolecules, resulting in tumor cell death. Samarium Sm 153 also emits gamma-photons that can be detected for external imaging.;

Alternative definition : NCI-GLOSS: A radioactive substance used in the treatment of bone cancer and bone metastases (cancers that have spread from the original tumor to the bone). Samarium 153 is a radioactive form of the element samarium. It collects in bone, where it releases radiation that may kill cancer cells. It is a type of radioisotope.;

UNII : 6Q1KA41UWM;

InChIKey : KZUNJOHGWZRPMI-AKLPVKDBSA-N;

CAS number : 15766-00-4;

Chemical formula : Sm;

Codes from synonyms : CDR0000045874; 457;

Details

Origin ID

C1809;

UMLS CUI

C0677942;

See also inter- (CISMeF)
- Sm-153 [LOINC part]
Semantic type(s)
- Element, Ion, or Isotope [UMLS semantic type]
- Indicator, Reagent, or Diagnostic Aid [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- SM 153 [LOINC Challenge]
- Samarium-153 [MeSH Supplementary Concept]
- Samarium-153 (substance) [SNOMED CT concept]
- Sm-153 [LOINC part]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- HemOnc Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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