NCIt definition : Comparative genomic hybridization (CGH) is a technique that allows the detection of
losses and gains in DNA copy number across the entire genome without prior knowledge
of specific chromosomal abnormalities. Comparative genomic hybridization utilizes
the hybridization of differentially labeled tumor and reference DNA to generate a
map of DNA copy number changes in tumor genomes. Comparative genomic hybridization
is an ideal tool for analyzing chromosomal imbalances in archived tumor material and
for examining possible correlations between these findings and tumor phenotypes. (from
Ried et al. J Mol Med 1997 75:801-14);
Currated CISMeF NLP mapping