Preferred Label : Spunoleucel;
NCIt synonyms : Allogeneic VSTs ALVR106; Allogeneic Multi-VSTs ALVR106; Allogeneic Multi-virus-specific T-cells ALVR106;
NCIt definition : A preparation of off-the-shelf (OTS), donor-derived T-lymphocytes that are specifically
reactive towards four community acquired respiratory viruses: respiratory syncytial
virus (RSV), influenza, parainfluenza virus (PIV), and human metapneumovirus (hMPV),
with potential antiviral activity. Upon infusion into allogeneic hematopoietic stem
cell transplant (HSCT), solid organ transplant (SOT) recipients or other immunocompromised
patients, spunoleucel provides virus-specific cellular immunity and causes specific
anti-viral effects against the four viruses RSV, influenza, PIV and hMPV. This may
prevent RSV, influenza, PIV and hMPV infection, and inhibits viral-associated diseases.;
UNII : EVQ94BW5G4;
Molecule name : ALVR-106; ALVR 106;
NCI Metathesaurus CUI : CL1663422;
Origin ID : C180636;
UMLS CUI : C5908094;
Semantic type(s)
- Cell [UMLS semantic type]
- concept_is_in_subset
