Preferred Label : Allogeneic AdV/CMV/EBV-specific T-lymphocytes;
NCIt synonyms : Allogeneic AdV/CMV/EBV Multi-virus-specific T Lymphocytes;
NCIt definition : A preparation of human leukocyte antigen (HLA)-matched or HLA-mismatched, allogeneic
CD4 and CD8 T-lymphocytes, ex vivo incubated with synthetic peptides of the viral
antigens of the three human viruses adenovirus (AdV), cytomegalovirus (CMV) and Epstein-Barr
virus (EBV), with potential antiviral activity. Upon administration of the allogeneic
AdV/CMV/EBV-specific T-lymphocytes after allogeneic hematopoietic stem cell transplantation
(HSCT), these T-lymphocytes may kill AdV, CMV, and/or EBV-infected cells, and may
prevent or reduce the severity of viral infections by these pathogens.;
NCI Metathesaurus CUI : CL1663060;
Origin ID : C180509;
UMLS CUI : C5556428;
Semantic type(s)
- Cell [UMLS semantic type]
- concept_is_in_subset
