Preferred Label : Anti-Senl-h19 CAR T Cells;
NCIt synonyms : Senl-h19 CAR T Cells; Senl-h19 CAR-T Cells;
NCIt definition : A preparation of T-lymphocytes that have been genetically modified to express a chimeric
antigen receptor (CAR) targeting the human tumor-associated antigen (TAA) CD19, with
potential immunostimulating and antineoplastic activities. Upon administration, anti-Senl-h19
CAR T cells target and bind to CD19-expressing tumor cells, thereby inducing selective
toxicity in CD19-expressing tumor cells. CD19 antigen is a B-cell specific cell surface
antigen expressed in all B-cell lineage malignancies.;
NCI Metathesaurus CUI : CL1662775;
Origin ID : C180381;
UMLS CUI : C5556332;
Semantic type(s)
- Cell [UMLS semantic type]
- concept_is_in_subset
