Preferred Label : Oncolytic Vaccinia Virus OVV-01;
NCIt synonyms : Oncolytic Virus OVV-01;
NCIt definition : An oncolytic vaccinia virus (VV), with potential immunomodulating and antineoplastic
activities. Upon intratumoral administration of the oncolytic vaccinia virus OVV-01,
the virus preferentially targets and infects tumor cells, thereby causing oncolysis.
In turn, the lysed tumor cells release various tumor-associated antigens (TAAs), which
induce an immune response against the tumor cells. This further kills tumor cells.;
Molecule name : OVV-01; C045; OVV 01;
NCI Metathesaurus CUI : CL1662468;
Origin ID : C179713;
UMLS CUI : C5555870;
Semantic type(s)
- Virus [UMLS semantic type]
- concept_is_in_subset
