Preferred Label : Fluorine F 18 Fluoropivalate;
NCIt synonyms : [18F]Fluoro-2,2-Dimethylpropionic Acid; 18F-fluoropivalate; [18F]FPIA; 3-18F-fluoro-2,2-dimethylpropionic Acid;
NCIt definition : A radioconjugate composed of fluoropivalate, a non-natural short-chain fatty acid
(SCFA), labeled with the positron-emitting radioisotope fluorine F 18, with potential
use as an imaging agent for tracing SCFA metabolism upon positron emitting tomography
(PET)/computed tomography (CT). Upon administration, fluorine F 18 FPIA is rapidly
taken up by tumor cells. This may allow for the visualization of tumor cells upon
PET/CT. SCFA is used as an energy source for cell growth and proliferation; tumor
cells take up SCFAs at a much higher rate than normal, healthy cells due to their
increased energy demand to allow for rapid tumor cell proliferation.;
NCI Metathesaurus CUI : CL1662421;
Origin ID : C179642;
UMLS CUI : C5555836;
Semantic type(s)
- concept_is_in_subset
