(R)-2-Hydroxyglutarate

Preferred Label : (R)-2-Hydroxyglutarate;

NCIt synonyms : (2R)-2-Hydroxypentanedioic Acid; D2HG; (R)-Hydroxyglutarate; (R)-2HG; D-2-HG; (R)-2-Hydroxyglutaric Acid; D-2HG;

NCIt related terms : D-2-Hydroxyglutarate;

NCIt definition : The R-enantiomer of alpha-hydroxyglutarate (2-HG) where the hydroxy group is attached to the right side of the asymmetric carbon furthest from the carbonyl. This isoform is the predominant form found in gliomas associated with the expression of isocitrate dehydrogenase (IDH) mutants. Therefore, measurement of the expression of the R-form may be correlated more closely with those diseases than measurement of total 2-HG.;

NCI Metathesaurus CUI : CL1661984;

Details

Origin ID

C179314;

UMLS CUI

C4068075;

Automatic exact mappings (from CISMeF team)
- D-2-hydroxyglutarate [LOINC component]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- D-2-hydroxyglutarate [LOINC component]
- D-2-hydroxyglutarate (substance) [SNOMED CT concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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