Preferred Label : CD8-depleted Non-engrafting HLA-mismatched Unrelated Donor Lymphocytes;
NCIt definition : A preparation of allogeneic lymphocytes from an HLA-mismatched donor that have been
selectively depleted of CD8 T-cells, with potential T-cell reconstitution purposes.
Upon infusion, the donor-derived CD8 -depleted lymphocytes may increase the levels
of CD4 T-cells (Teffs) and promote T-cell reconstitution. The infusion of donor lymphocytes
depleted of CD8 T-cells may reduce the risk of inducing graft-versus-host disease
(GVHD) compared to the infusion of non-CD8-depleted T-cells.;
NCI Metathesaurus CUI : CL1661901;
Origin ID : C179290;
UMLS CUI : C5555588;
Semantic type(s)
- Cell [UMLS semantic type]
- concept_is_in_subset
