Preferred Label : CD19-targeted CAR T2 Cells;
NCIt synonyms : CD19-CAR-T2 Cells;
NCIt definition : A preparation of T-lymphocytes that have been genetically modified to express a chimeric
antigen receptor (CAR) targeting the tumor-associated antigen (TAA) CD19, with potential
immunostimulating and antineoplastic activities. Upon administration, CD19-targeted
CAR T2 cells target and bind to CD19-expressing tumor cells, thereby inducing selective
toxicity in CD19-expressing tumor cells. CD19 antigen is a B-cell specific cell surface
antigen expressed in all B-cell lineage malignancies.;
NCI Metathesaurus CUI : CL1661890;
Origin ID : C179281;
UMLS CUI : C5555580;
Semantic type(s)
- Cell [UMLS semantic type]
- concept_is_in_subset
