Preferred Label : Indium In 111 FPI-2058;
NCIt synonyms : 111Indium-labeled IPN01087; 111 In-3BP-227; (111In)-IPN01087; 111In-IPN01087; Indium In 111 3BP-227; [111In]-FPI-2058; Indium In 111 IPN01087;
NCIt definition : A radioconjugate consisting of the neurotensin receptor type 1 (NTR1; NTSR1) antagonist,
IPN01087 (3BP-227) that is linked to the radioisotope indium In 111, with potential
imaging activity during single photon emission computed tomography (SPECT)/computed
tomography (PET/CT). Upon administration, indium In 111 IPN01087 targets and binds
to NTR1 expressed on certain tumor cells. Upon binding and radioimaging, NTR1-expressing
tumor cells can be visualized and the biodistribution of IPN01087 can be assessed.
NTR1, a G-protein coupled receptor, is highly expressed in ductal pancreatic adenocarcinoma
but not in normal pancreatic tissue.;
NCI Metathesaurus CUI : CL1661915;
Origin ID : C179272;
UMLS CUI : C5854868;
Semantic type(s)
- concept_is_in_subset
- has_target
