UNC93B1 wt Allele

Preferred Label : UNC93B1 wt Allele;

NCIt synonyms : Unc-93B1; IIAE1; Unc-93 Homolog B1 (C. elegans) Gene; Unc93 (C. elegans) Homolog B1 Gene; UNC93B; UNC93, C. elegans, Homolog of, B1 Gene; Unc93 Homolog B1, TLR Signaling Regulator Gene; UNC93; Unc93 Homolog B1 Gene; Unc-93 Homolog B1, TLR Signaling Regulator wt Allele;

NCIt definition : Human UNC93B1 wild-type allele is located in the vicinity of 11q13.2 and is approximately 13 kb in length. This allele, which encodes protein unc-93 homolog B1, plays a role in transport of a subset of certain toll-like receptors from the endoplasmic reticulum to endolysosomes. Mutation of the gene is associated with susceptibility to herpes simplex infection-induced encephalitis type 1.;

NCI Metathesaurus CUI : CL1648469;

GenBank Accession Number : AJ271326;

Details

Origin ID

C179153;

UMLS CUI

C5551283;

Automatic exact mappings (from CISMeF team)
- unc-93 homolog B1, TLR signaling regulator [ORDO Gene]
OMIM relation
- Unc93 homolog b1, tlr signaling regulator [OMIM gene]
See also inter- (CISMeF)
- Encephalopathy, acute, infection-induced (herpes-specific), susceptibility to, 1 [OMIM Phenotype]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 11q13.2 [NCIt concept]
gene_plays_role_in_process
- Immunity [NCIt concept]
- Intracellular Transport [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Subcellular Protein Targeting [NCIt concept]
- Transport Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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