Tumor Necrosis Factor Receptor 1-Associated DEATH Domain Protein

Preferred Label : Tumor Necrosis Factor Receptor 1-Associated DEATH Domain Protein;

NCIt synonyms : TNF Receptor-Associated Protein with a Death Domain; TNFRSF1A-Associated via Death Domain; TRADD Protein; TRADD; Tumor Necrosis Factor Receptor-1-Associated Protein; TNFR1-Associated DEATH Domain Protein;

NCIt definition : Tumor necrosis factor receptor type 1-associated DEATH domain protein (312 aa, 34 kDa) is encoded by the human TRADD gene. This protein plays a role in apoptosis and the activation of NF-kappa-B signaling pathways.;

Details

Origin ID

C17907;

UMLS CUI

C5441636;

OMIM relation
- Tumor necrosis factor receptor 1-associated death domain protein [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- TNF Receptor-Associated death domain protein [MeSH Descriptor]
- TNF Receptor-Associated death domain protein [MeSH concept]
gene_encodes_gene_product
- Adaptor Signaling Protein Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
- TRADD Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- Apoptosis Promoter [NCIt concept]
gene_product_has_structural_domain_or_motif
- Death Domain [NCIt concept]
- Nuclear Localization Signal [NCIt concept]
gene_product_is_element_in_pathway
- Adipocytokine Signaling Pathway [NCIt concept]
- Apoptosis Pathway [NCIt concept]
- Caspase Cascade in Apoptosis [NCIt concept]
- Ceramide Signaling Pathway BioCarta [NCIt concept]
- Ceramide Signaling Pathway PID [NCIt concept]
- DR3 and DR4/5 Mediated Apoptosis Pathway [NCIt concept]
- HIV-1 Nef: Negative Effector Pathway for Fas and TNF-Alpha [NCIt concept]
- HIV-I Nef in Apoptosis Pathway [NCIt concept]
- MAPKinase Signaling Pathway [NCIt concept]
- NFKB Signaling Pathway [NCIt concept]
- RELA Pathway [NCIt concept]
- RIG-I-Like Receptor Signaling Pathway [NCIt concept]
- SODD/TNFR1 Signaling Pathway [NCIt concept]
- TNF Receptor Family Signaling Pathway [NCIt concept]
- TNF Stress Related Signaling Pathway [NCIt concept]
- TNFR1 Signaling Pathway [NCIt concept]
- TRAIL Signaling Pathway [NCIt concept]
- p38 MAPK Signaling Pathway BioCarta [NCIt concept]
gene_product_plays_role_in_biological_process
- Positive Regulation of Apoptosis [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- Subcellular Protein Targeting [NCIt concept]

Keyword's position in hierarchy(ies) :

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