SSEA-4 Antigen

Preferred Label : SSEA-4 Antigen;

NCIt synonyms : SSEA4; Stage-Specific Embryonic Antigen 4; SSEA-4; Stage Specific Embryonic Antigen 4;

NCIt definition : A ganglioside comprised of a glycosphingolipid (GSL) containing a terminal sialic acid residue (N-acetylneuraminic acid) that is synthesized by the enzyme ST3 beta-galactoside alpha-2,3-sialyltransferase 2 (ST3GAL2). This epitope is expressed on the surface of human embryonic stem cells and human embryonic germ cells. Its expression is turned off once these cells differentiate during development. Reactivation of expression is found on the surface of embryonal carcinoma cells.;

NCI Metathesaurus CUI : CL1648089;

Details

Origin ID

C178548;

UMLS CUI

C0286848;

Automatic exact mappings (from CISMeF team)
- stage-specific embryonic antigen-4 [MeSH Supplementary Concept]
Semantic type(s)
- Immunologic Factor [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- stage-specific embryonic antigen-4 [MeSH Supplementary Concept]
- stage-specific embryonic antigen-4 [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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