Preferred Label : Multi-kinase Inhbitor AIV001;
NCIt definition : A prolonged-release multi-kinase inhibitor, with potential anti-angiogenic, anti-fibrotic
and antineoplastic activities. Upon intradermal or intratumoral administration, AIV001
targets and binds to several kinases, including vascular endothelial growth factor
receptor (VEGFR), and inhibits multiple pathways involved in neovascularization, fibrosis,
abnormal cell proliferation and inflammation. This may reduce dermal neovascularization
and fibroplasia during wound healing and scarring, reduce inflammation and fibrosis
associated with certain skin conditions, and may reduce neovascularization and cell
proliferation associated with certain types of cancers.;
Molecule name : AIV-001; AIV 001;
NCI Metathesaurus CUI : CL1647828;
Origin ID : C178338;
UMLS CUI : C5554963;
Semantic type(s)
- concept_is_in_subset
- has_target
