Preferred Label : Personalized Neoantigen Plasmid DNA Melanoma Vaccine EVX-02;
NCIt synonyms : Melanoma Vaccine EVX-02; Personalized Melanoma Vaccine EVX-02; Plasmid DNA Melanoma Vaccine EVX-02;
NCIt definition : A plasmid DNA melanoma vaccine composed of DNA plasmid encoding multiple, melanoma
patient-specific neoepitopes, which are highly immunogenic tumor associated antigens
(TAAs), with potential immunostimulatory and antineoplastic activities. Upon intramuscular
(IM) administration of personalized neoantigen plasmid DNA melanoma vaccine EVX-02,
the plasmid DNA is taken up by antigen-presenting cells (APCs) and the expressed neoepitopes
induce cytotoxic T-lymphocyte (CTL)-mediated immune responses against melanoma cells
expressing these specific TAAs.;
Molecule name : EVX 02; EVX-02;
NCI Metathesaurus CUI : CL1647819;
Origin ID : C178317;
UMLS CUI : C5554943;
Semantic type(s)
- concept_is_in_subset
