Preferred Label : BG8 IHC Staining Method;
NCIt synonyms : Anti-LeY BG8 Staining Method; BG-8 Staining Method; BG8 Antibody Staining Method; BG8 Staining Method; Anti-Anti-Lewis Y BG8 Staining Method; Antibody BG8 Staining Method; Anti-Anti-Lewis-Y BG8 Staining Method;
NCIt related terms : BG8; Lewis Y Antigen Blood Group 8;
NCIt definition : An immunohistochemical technique utilizing the mouse monoclonal antibody BG8, which
is directed against the type 2 fucosylated antigen Lewis Y (LeY). BG8 specifically
binds to LeY, a blood group Lewis carbohydrate determinant expressed on certain glycolipids
and glycoproteins. In healthy subjects, LeY is expressed in low levels by a few types
of epithelial cells; however, it is aberrantly expressed in high levels in many carcinomas.
This method is use in the detection of certain tumors, such as carcinomas of the breast,
lung, and colon. Additionally, it may distinguish neoplasms derived from mesothelium
from other epithelial-derived neoplasms.;
NCI Metathesaurus CUI : CL1647890;
Origin ID : C178240;
UMLS CUI : C5554891;
Automatic exact mappings (from CISMeF team)
- Semantic type(s)
- concept_is_in_subset
