Preferred Label : D2-40 IHC Staining Method;
NCIt synonyms : D2-40 Antibody Staining Method; Anti-PDPN D2-40 Staining Method; D2-40 Staining Method; Anti-Podoplanin D2-40 Staining Method; Antibody D2-40 Staining Method;
NCIt related terms : D2-40 Monoclonal Antibody; D2-40;
NCIt definition : An immunohistochemical technique utilizing the mouse monoclonal IgG1 antibody D2-40,
which is directed against the human O-linked sialoglycoprotein podoplanin (PDPN).
D2-40 specifically binds to PDPN, a protein that is selectively expressed in normal
lymphatic endothelium as well as in vascular lesions of lymphatic origin. This staining
method can detect aberrant expression of lymphatic epithelium, which is associated
with lymphangioma, Kaposi sarcoma, epithelioid mesothelioma and seminoma.;
NCI Metathesaurus CUI : CL1647892;
Origin ID : C178238;
UMLS CUI : C5552773;
Automatic exact mappings (from CISMeF team)
- Semantic type(s)
- related_to_genetic_biomarker
