" /> COVID-19 Vaccine MVC-COV1901 - CISMeF





Preferred Label : COVID-19 Vaccine MVC-COV1901;

NCIt synonyms : SARS-CoV-2 Spike Protein Plus Adjuvant CpG 1018; SARS-CoV-2 Vaccine MVC-COV1901;

NCIt definition : A vaccine composed of a recombinant form of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) spike protein (SP) combined with a synthetic CpG motif-based oligodeoxynucleotide (CpG ODN) vaccine adjuvant, CpG 1018, with potential immunomodulating and anti-COVID-19 activities. Upon administration of COVID-19 Vaccine MVC-COV1901, the SARS-CoV-2 SP activates the immune system to produce anti-SARS-CoV-2 SP antibodies and T-cell responses against SARS-CoV-2 SP. The antibodies recognize the SP and kill SARS-CoV-2. This prevents SARS-CoV-2 infection. SP, usually found on the surface of SARS-CoV-2, plays an essential role in the infection pathway of the SARS-CoV-2 virus. The adjuvant strongly stimulates both T-cell and antibody immune responses when combined with the recombinant SARS-CoV-2 SP.;

Molecule name : MVC-COV1901; MVC COV1901;

NCI Metathesaurus CUI : CL1651009;

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22/05/2024


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