Preferred Label : Donor Derived HIV-Specific T-cells with Non-escaped Epitope Targets;
NCIt synonyms : DD-HST-NEETs; DD HST-NEETs;
NCIt definition : A preparation of ex vivo expanded donor-derived (DD) human immunodeficiency virus
(HIV)-specific T-cells (HSTs) with non-escaped epitope targets (NEETs), that can potentially
be used to eliminate HIV-infected cells and eradicate HIV. Upon administration, DD
HST-NEETs target and kill HIV-infected cells, thereby eradicating HIV. HST-NEETs recognize
multiple conserved, non-escaped HIV epitopes and their common variants, which is important
in killing latently infected cells and could reduce viral escape.;
NCI Metathesaurus CUI : CL1647664;
Origin ID : C178128;
UMLS CUI : C5554856;
Semantic type(s)
- Cell [UMLS semantic type]
- concept_is_in_subset
