Preferred Label : Iron Chelating Agent SP-420;
NCIt synonyms : (4S)-4,5-Dihydro-2-[2-hydroxy-4-[2-(2-methoxyethoxy)ethoxy]phenyl]-4-methyl-4-thiazolecarboxylic
Acid; Chelating Agent SP-420; Iron Chelator SP-420;
NCIt related terms : SP-420;
NCIt definition : An orally bioavailable iron-chelating agent and derivative of desferrithiocin, with
iron chelating and protective activities in diseases of iron overload. Upon oral administration,
the iron chelating agent SP-420 targets, binds to and chelates free iron. This induces
the excretion of iron, prevents iron accumulation and prevents cellular and/or tissue
damage associated with iron overload.;
UNII : WBX54NZ436;
CAS number : 911714-45-9;
Molecule name : SP 420; SP-420;
NCI Metathesaurus CUI : CL1647645;
Origin ID : C178064;
UMLS CUI : C4548287;
Semantic type(s)
UMLS correspondences (same concept)
- SP-420 [MeSH Supplementary Concept]
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