M Protein - CISMeF

Preferred Label : M Protein;

NCIt synonyms : Monoclonal immunoglobulin; M Proteins; Myeloma Protein; M Component; M-Protein; Paraprotein; Spike Protein;

NCIt related terms : monoclonal protein;

NCIt definition : A protein complex comprised of two heavy chains and two light chains. Monoclonal immunoglobulin (M protein) is found in abundance in patients who have multiple myeloma. The protein is not produced in response to an antigen, but it is expressed in malignant plasma cells and excreted into the blood and urine.;

Alternative definition : NCI-GLOSS: An antibody found in unusually large amounts in the blood or urine of people with multiple myeloma and other types of plasma cell tumors.;

Codes from synonyms : CDR0000411378; CDR0000046299;

Details

Origin ID

C17788;

UMLS CUI

C0700271;

Currated CISMeF NLP mapping
- M-proteins (Myeloma) [MeSH concept]
- M-proteins (Myeloma) [MeSH Supplementary Concept]
- Protein.monoclonal [LOINC component]
- protein M (glycoprotein) [MeSH concept]
- protein M (glycoprotein) [MeSH Supplementary Concept]
See also inter- (CISMeF)
- Monoclonal immunoglobulin (substance) [SNOMED CT concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- Protein.monoclonal [LOINC component]
- multiple myeloma M-proteins [MeSH concept]
- multiple myeloma M-proteins [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Immunoprotein Gene [NCIt concept]
gene_product_has_biochemical_function
- Antibody [NCIt concept]
gene_product_has_chemical_classification
- Protein or Riboprotein Complex [NCIt concept]
gene_product_plays_role_in_biological_process
- Antigen Binding [NCIt concept]
- Immune Response Process [NCIt concept]
- Immune System Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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