ACTB/FOSB Fusion Gene

Preferred Label : ACTB/FOSB Fusion Gene;

NCIt synonyms : ACTB-FOSB Fusion Gene; Actin Beta/FosB Proto-Oncogene Fusion Gene; Actin Beta-FosB Proto-Oncogene Fusion Gene; ACTB::FOSB Fusion Gene;

NCIt definition : A fusion gene that results from a chromosomal translocation t(7;19)(p22;q13) which fuses the exon 3 of the ACTB gene with exon 2 of the FOSB gene. This rearrangement is associated with pseudomyogenic hemangioendothelioma and deregulation of protein fosB transcriptional activation activity.;

NCI Metathesaurus CUI : CL1643443;

PubMed : 30256258;

Details

Origin ID

C177673;

UMLS CUI

C5447935;

Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_encodes_gene_product
- ACTB/FOSB Fusion Protein [NCIt concept]
gene_involved_in_pathogenesis_of_disease
- Pseudomyogenic Hemangioendothelioma [NCIt concept]
gene_mapped_to_disease
- Childhood Pseudomyogenic Hemangioendothelioma [NCIt concept]
- Pseudomyogenic Hemangioendothelioma [NCIt concept]
related_to_genetic_biomarker
- ACTB Gene [NCIt concept]
- FOSB Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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