NCIt definition : A monoclonal antibody directed against human epidermal growth factor receptor (EGFR)
with potential antineoplastic activity. Upon administration, anti-EGFR monoclonal
antibody ZZ06 targets, binds and prevents the activation of EGFR. This inhibits EGFR-mediated
signaling and proliferation of EGFR-expressing tumor cells. EGFR, a member of the
epidermal growth factor receptor family, is overexpressed on various tumor cell types.;