Superficial CD34-Positive Fibroblastic Tumor

Preferred Label : Superficial CD34-Positive Fibroblastic Tumor;

NCIt synonyms : SCD34FT;

NCIt definition : A low-grade neoplasm of the skin and subcutaneous tissue that is characterized by the presence of CD34-positive spindle cells with abundant, eosinophilic, granular to glassy cytoplasm, low mitotic activity, marked nuclear pleomorphism, and frequent keratin immunoreactivity. Rearrangement of PRDM10 gene is often present. It manifests as a slow-growing, painless mass of the superficial soft tissues, with a predilection to the lower extremities. Rare cases present as deep-seated tumors. The prognosis is excellent.;

Neoplastic status : Undetermined;

NCI Metathesaurus CUI : CL1643287;

Details

Origin ID

C177324;

UMLS CUI

C5447696;

Disease excludes normal cell origin
- Epithelial Cell [NCIt concept]
Disease may have findings
- Cytokeratin-Positive Neoplastic Cells Present [NCIt concept]
Excludes anatomical site(s)
- Bone [NCIt concept]
Has associated anatomic sites
- Connective and Soft Tissue [NCIt concept]
- Integumentary System [NCIt concept]
- Skin [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
disease_excludes_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
disease_has_abnormal_cell
- Neoplastic Cell [NCIt concept]
disease_has_finding
- CD34-Positive Neoplastic Cells Present [NCIt concept]
- Cutaneous Involvement [NCIt concept]
- Locally Aggressive Lesion [NCIt concept]
- Low Mitotic Activity [NCIt concept]
- Nuclear Pleomorphism [NCIt concept]
- Tissue Differentiation Uncertain [NCIt concept]
disease_has_grade
- Low Grade [NCIt concept]
disease_has_normal_tissue_origin
- Soft Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Skin [NCIt concept]

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